- Zadok (High Priest), the first high priest of the Israelites in Jerusalem after it was conquered by David. Also written as Zadoq (Ts+D+Q).
- The father of Jerusha, who was wife of King Uzziah, and mother of King Jotham (2 Kings 15:33; 2 Chr. 27:1).
- "The scribe" set over the treasuries of the temple by Nehemiah along with a priest and a Levite (Nehemiah 13:13).
- The son of Baana, one of those who assisted in rebuilding the wall of Jerusalem (Neh. 3:4).
- The Hebrew term for Sadducees (Zadokim), the Priestly sect during the time of the Second Temple
- A founder of the Zealots along with Judas of Galilee
- Rabbi Tzadok was a respected member of the sages in Jerusalem in the first century. He is famous for a fast he began 40 years before the destruction of the Temple in 70 CE wherein he would eat and live off of one fig per day only.
- Rachel Zadok is a South-African writer currently based in London, England.
- Erez Zadok is the current maintainer of the Berkeley Automounter
- Haim Yosef Zadok (1913-2002) was an Israeli jurist and politician.
- Zadok Allen is a character in the H. P. Lovecraft story, The Shadow Over Innsmouth.
- Avi Zadok is the head of Mossad in story The Last Jihad by Joel C. Rosenberg
- Zadok, named after the biblical figure, is a golem from the webcomic One Over Zero.
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