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Yitzchak Isaac of Zidichov (1805-1873) was a noted Hasidic rabbi. He was the son of Rabbi Yisachar Barish, who was the brother of Rabbi Tzvi Hirsh of Zidichov (1763-1831). Rabbi Yitzchak Isaac was a close disciple of Rabbi Tzvi Hirsh of Zidichov until the latter's death. He later studied under the leader of the Belz Rabbi Shalom of Belz.