- Saint Lawrence (225–258), the Christian martyr, after whom all others are named
- Saint Laurence of Canterbury (d. 619), second Archbishop of Canterbury
- Lorcán Ua Tuathail (1128–1180), also known as St Laurence O'Toole
- Saint Lawrence of Brindisi (1559–1619), Doctor of the Church
- Saint Lawrence Ngon and Lawrence Huong Van Nguyen of the Vietnamese Martyrs
- Laurent-Marie-Joseph Imbert, one of the Korean Martyrs
- Lorenzo Giustiniani (1381-1456)
- Lorenzo Ruiz (1600-1637), Chinese-Filipino among the 16 Martyrs of Japan
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