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The name may refer to one of the three men named Uz who are mentioned in the Bible.
The word may also be related etymologically to the word oz, meaning 'east'. In the Book of Job (1:3), Job is described as "the greatest of all the people of the East."
Uz is sometimes identified with the kingdom of Edom, roughly in the area of modern-day southwestern Jordan and southern Israel. Lamentations 4:21 reads, "Rejoice and be glad, O daughter of Edom, that dwellest in the land of Uz."