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Panicker was born on April 1, 1924 at Karichal. His father was K. G. Thomas Panicker and his mother was Achiyamma Thomas Panicker and he was the eledest of seven children.
Panicker is the grand Nephew of the Archbishop Geevarghese Mar Ivanios, the founder of Malankara Catholic Church, who is also known as the 'Newman of India'. He completed his higher secondary education under the guidance of Kayinikkara Kumara Pillai. After the school eduction he joined St. Aloysius Seminary, Trivandrum. He continued the philosophical and theological studies at Papal Seminary, Kandy, Sri Lanka. He was ordained a priest on August 24, 1949. He had his higher studies in Catholic University of America. He took doctorate in English Literature.
Panicker started his teaching career as a lecturer in Mar Ivanios College. He became the Vice Principal of the college in 1959. And he was the principal of Mar Ivanios College during 1961 - 1979. 
He was the Rector and President of St. Joseph's Pontifical Institute , Mangalapuzha, Aluva in 1979 - 1985. Then he became the Rector of St. Mary’s Malankara Major Seminary. He was the Dean of Studies of St. Ephrem Ecumenical Research Institute.
Panicker died on December 28, 2008 at Kollam. His body was interred in Syro-Malankara Catholic Church at Paranthal, Adoor. Moran Mor Baselios Cleemis Catholicos led the funeral service. He was buried near his parents as he requested. Panicker died on the same day as his father, Thomas Panicker, did 32 years ago.