According to the tradition of the Observant Franciscans the proto-friary of the Irish Province of the Order was founded at Youghal by Maurice Fitz Gerald in 1224. The Irish Province of the Franciscans was formally erected at the general chapter of Assisi in 1230. The same chapter also appointed Richard of Ingworth as first minister provincial who appears to have taken up residence in Youghal. It was probably from this house that an important early friary, dedicated to St. Thomas à Becket, was established at Buttevant. It was to be the only Franciscan house in North Cork. The Annals of the Four Masters record that it was founded and endowed in 1251 by David Óg de Barry. The townsland of Lagfrancis was assigned as the glebe for its mensa.
By 1324 Buttevant friary consisted of a community of Irish and Anglo-Norman friars and was sufficiently important to maintain its own studium, or house of studies. Racial tensions, however, troubled the community. In 1327 the commission established by Pope John XXII in 1317 to investigate the Irish Province of the Order determined the transfer of the Gaelic lector from Buttevant to one of its Gaelic friaries. In 1325, the general chapter of the Order, held at Lyons, was informed that the obedience of the friary of St. Thomas at Buttevant had been transferred to the recently erected custody of Cork, thereby taking the house out of Irish control and subjecting it to that of the Anglo-Norman custody of Cork. 
The Rotulus Pipae Cloynensis notes that by indenure, made on 9 May 1402 in the vestibule of the Friars Minor of Buttevant, Sir John de Barry, Knight, Lord of Olethan and Muscrydonygan, agreed with Gerald, Lord Bishop of Cloyne, "that henceforth he [would] not put, either by himself or by another in his name, bonys, conwys, guydagia or pedagia upon his [the Bishop's] castle and lordship of Kilmaclenine and the tenants staying and dwelling in the same". Reference here to the vestibule of the friary is an indication that the law courts, as in all of medieval Europe, operated at the door of the friary church, which is likely to have been painted red - as is still the case, for example, with the "Rothertor" of the Cathedral in Paderborn. In the medieval burgage of Buttevant, the friary porch was the place to make legal agreements, renew or grant leases on Lady Day and Michelmas, swear fealty, do homage and contract marriage in the form described, for instance, in Johann Burchard's account of the nuptials of Don Joffré de Borgia and Donna Sancia de Aragon before the door of the chapel royal in the Castel Nuovo in Naples on 11 May 1494. The Rotulus Pipae Cloynensis makes clear that the same legal functions happened at the front door of the parish church of St. Briget.
At the time of its dissolution, c. 1540, the examining jurors, William Coppinger, William Meagh, Nicholas Lombard and Thomas Vernon, certified that the Franciscan friary at Buttevant consisted of the friary church and conventual buildings with no surplus appurtenances; a garden and cemetery containing an acre and a half of ground worth 6 shillings and 8 pence; and a watermill worth 30 shillings, bringing the total extent of its property to 36 shillings and 8 pence.
In 1570, Lord James de Barry, 4th. Viscount Buttevant, received a lease, to hold for twenty-one years, of "the site of the house of the friars at Killnamullagh, alias Buttevante, Co. Cork, with its appurtenances at an annual rent of 16 shillings and 8 pence". At the outbreak of the Desmond Rebellions, Viscount Buttevant joined the rebels and in the subsequent confiscations of his estates, the friary in Buttevant, together with its glebe, passed into the hands of Edmund Spencer in the Munster Plantation, one of the first of the Plantations of Ireland.
While there is some evidence to suggest that the friary was re-ccupied as early as the accession of James I, Father Donatus Mooney's Provincial Report of 1617/1618 establishes that the friary certainly had once again reverted to Lord Barry by 1615, or perhaps earlier, indicating that the 1570 lease of Buttevant friary from the crown had been renewed in favour of Lord Barry, albeit with conditions concerning the occupation of the conventual buildings by the friars. Two friars still continued to live in the town and officiated at burials. Father Mooney states that the friars "may not live in the convent because the brother of the late Lord de Barry is bound under pain of heavy fine to heretics, not to permit the friars to live there. He is a Catholic, and is unwillingly forced to act thus, for he holds the monastery from the King, and in other respects, as far as he can, favours the friars. His name is Lord John de Barry" (Bibliothèque Royale, Brussels).
The Brussels manuscript mentions that in 1615 the large church of the friary "still remains, roofed with wooden tiles, and in it are many of the tombs of the nobility. The friary buildings were not well-proportioned, but they were spacious and numerous".
In March 1607, the Protestant bishop of Cork, William Lyon, complained to the Lord Deputy that there was "an abbey at Buttevant where divers friars in their habits go up and down the country to the grief of the godly, in a kingdom where so godly a king as his Majesty reigneth. The warden's name is, as they call him, Conor M'Morice". The complaint also contains the names of the other friars then at Buttevant: "William Foy, Nicholas Sheynan and WIlliam Fer[...]" and notes that in the abbey there were "continual and daily masses and assemblies and conventicles, little for the good of the King and the State".
A further pertinent manuscript, the Brevis Synopsis Provincialis F.F. Minorum compiled between 1626 and 1629 by Father Francis Matthews, is preserved in the archive of the Irish Franciscan Convent of St. Isidore in Rome. It make two references to the friary in Buttevant. It recounts that "in the reign of Queen Elizabeth of England, the friars were at times expelled from thence; some were captured and imprisoned. Although the statues in the church were broken the church itself was left standing because of the tombs of the nobility therein; the convent buildings were, however, destroyed, and yet some of the friars have not ceased to live unto this day (1629) either in the convent or in its neighbourhood. The original founder of the convent was Lord Barry, Viscount of Buttevant, whose family, which has now branched out into the Counts of Barrymore, and other most noble families, have their tombs in the same convent, in which also Lord MacDonagh and many nobles of adjacent estates have been buried from ancient days".
After the outbreak of the Irish Rebellion of 1641, the Franciscan community in Buttevant welcomed the Confederate Catholic army of Lord Mountgarret - one of the leading Catholic magnates in the south of Ireland. The guardian, Father Boetius Egan, accompanied the army and took part in the Confederate Parliament in Kilkenny in 1642. In the ensuing war in Munster, the Protestant commander, Murrough O'Brien, Earl of Inchiquin, assembled his English Parliamentarian army in Buttevant and burned the friary church. Inchiquinn's conduct in the war earned him the nickname Murchadh na dTóiteán - "Murrough of the Burnings".
Robert Bettesworth, High Sheriff of Cork, reported on 26 November 1731: "There is but one friary in the county and that is in or near Buttevant. I could never hear of what number of fryers it consisted". Again, in the Abstract of the State of Popery in the Diocese of Cloyne compiled and presented to the House of Lords in 1731 it was noted that in the parish of Buttevant there was "one old Mass House. One popish priest. Convents of fryers and nuns; a thatched house within the precincts of the old abbey wherein one or two old fryers have dwelt some time past. One of these was lately dead".
An obituary list of the Clergy of the Diocese of Cloyne, compiled from memory by Bishop William Coppinger (1791-1830), dating from c. 1820, contains the names of those who must have been the last members of the Franciscan community at Buttevant Friary. Unfortunately the list was not written in chronological succession which makes it almost impossible to establish the exact dates of death of the four Franciscan friars mentioned in it. Bishop Coppinger merely states: "Pat Daly, a [Franciscan] [Friar] of Buttevant died of gout and scurvy; Pat O'Neill, a [Franciscan] [Friar] of Buttevant died of a fever in Cork; David Roche, a [Franciscan] [Friar] of Buttevant, of exemplary conduct, died of a fever in Buttevant; and Daniel McAuliffe, a [Franciscan] [Friar] of Buttevant, unemployed and turned horse jobber, died old". By 1820, the Franciscan presence in Buttevant had ended after almost six hundred years.
Samuel Lewis' Topographical Dictionary of Ireland (1837) notes the following of the Franciscan Friary at Buttevant: " The ruins of the abbey are finely situated on the steep bank of the river Awbeg, and consist chiefly of the walls of the nave, chancel, and some portions of the domestic buildings; the upper part of the central tower, supported on arches of light and graceful elevation, fell down in 1814; the tomb of the founder, David de Barry, is supposed to be in the centre of the chancel, but is marked only by some broken stones which appear to have formed an enclosure. On the south side of the nave are the remains of a finely proportioned chapel, in which, and also in the nave and chancel, are numerous tombs and inscriptions to the memory of the Barrys, Fitzgeralds, Lombards, and others".