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Alfredo Pacini (February 10, 1888—December 23, 1967) was an Italian Cardinal of the Roman Catholic Church. He served as Nuncio to Switzerland from 1960 to 1967, and was elevated to the cardinalate in 1967.
Alfredo Pacini was born in Capannori, and studied at the seminary in Lucca before being ordained to the priesthood on July 25, 1913. He then did pastoral work in the Archdiocese of Lucca and taught at its seminary until 1915, when he became a military chaplain during World War I. After resuming his work in Lucca, Pacini was raised to the rank of Honorary Chamberlain of His Holiness on October 8, 1924. He served as secretary (1924-1928) and auditor (1928-1933) of the nunciature to Yugoslavia. From 1935 to 1944, he was auditor of the Polish nunciature. He then became Domestic Prelate of His Holiness on September 3, 1935, and counselor of the nunciature to France in 1944.
On April 23, 1946, Pacini was appointed Nuncio to Haiti and Santo Domingo and Titular Archbishop of Germia by Pope Pius XII. He received his episcopal consecration on the following June 11 from Archbishop Angelo Roncalli, with Archbishop Louis Le Hunsec, CSSP, and Bishop Stanislas Courbe serving as co-consecrators, in Paris. Pacini was later named Nuncio to Uruguay on April 23, 1949, and Nuncio to Switzerland on February 4, 1960. From 1962 to 1965, he attended the Second Vatican Council.